The new technique uses autologous stem cells derived from a small sample fat and give the original anatomical structure of the bone.
Using this, scientists able to show that in a clinical-size porcine model of jaw repair, the bone grown in vitro and then implanted can regenerate a large defect and also mechanical function. The quality of the regenerated tissue, including vascularisation with blood perfusion, exceeds then using other approach.
Significance:
It improve regenerative medicine options and treatments suffering with craniofacial defects.
It also give opportunity for new scientific research where researchers can use cartilage layer in the bio-engineered living bone tissue to study bone regeneration in complex defects of the head and face.
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